Which of the following Is Not a Stop Codon?

Author

Reads 294

Library with lights

There are three stop codons in the genetic code: UAG, UAA, andUGA. The term "stop codon" refers to the sequence of nucleotides UAG, UAA, or UGA, which signals the end of protein synthesis. When any of these codons is encountered by the ribosome during translation, protein synthesis ceases.

The stop codons were originally identified in experiments with bacteria. In these experiments, it was shown that if a DNA sequence coding for a protein was inserted between two genes, the proteins encoded by the genes would be produced. However, if one of the stop codons was inserted between the two genes, protein synthesis would stop and no protein would be produced.

While stop codons are important for Polio, it is not the only disease stopped by these codons. Other diseases stopped by the stop codons include: SARS, HIV, and Ebola.

Discover more: Arithmetic Sequence

What is a stop codon?

A stop codon is one of the three possible ways to end a gene's coding sequence. The other two are the start codon and the opal codon. Stop codons are also known as termination codons. UGA, UAA, and UAG are the most common stop codons in eukaryotes. In prokaryotes, the most common stop codon is actually UAG, which is also known as the amber codon.

When a stop codon is reached, translation of the mRNA template by the ribosome ceases. This causes the release of the ribosome from the mRNA template. In bacteria, which lack a membrane-bound nucleus, protein synthesis usually stops immediately after the release of the ribosome. In eukaryotes, however, protein synthesis may continue for a short time if another start codon is nearby in the mRNA template. This results in the production of a truncated protein that is usually nonfunctional.

stop codons do not code for any amino acids, they simply signal the end of protein synthesis. Stop codons were first discovered in bacteria by Christian Anfinsen in 1961. He found that three codons, UAG, UAA, and UGA, did not code for any known amino acids, and he proposed that they signaled the end of protein synthesis.

So, to recap, a stop codon is a sequence of three nucleotides that does not code for an amino acid. Stop codons are also known as termination codons. UGA, UAA, and UAG are the most common stop codons in eukaryotes. In prokaryotes, the most common stop codon is UAG. Stop codons do not code for any amino acids, they simply signal the end of protein synthesis.

What are the three stop codons?

The three stop codons are the sequence of codons that tell the ribosome to stop translating the mRNA. The three codons are UAG, UAA, andUGA. These codons are also known as the "amber," "ochre," and "opal" codons, respectively. Each codon corresponds to a specific amino acid, and when one of these codons appears in the sequence, the ribosome will add the amino acid to the protein chain and then stop translating.

A stop codon is a sequence of three nucleotides that does not code for an amino acid and signals the end of protein synthesis by the ribosome. In RNA, the three nucleotide sequence UAG is known as the amber codon, UAA is known as the ochre codon, and UGA is known as the opal codon. In DNA, the amber codon is TAG, the ochre codon is TAA, and the opal codon is TGA. Stop codons are also referred to as termination codons.

The stop codons were first discovered in genetic studies of bacteriophage T4, which infects the bacterium Escherichia coli. Studies of the T4 phage showed that there are three codons that do not code for an amino acid, and that these codons serve as stop signals for protein synthesis. The three codons are UAG, UAA, and UGA.

The stop codons are important for two reasons. First, they ensure that proteins are synthesized to the correct length. If a stop codon is not present, the ribosome will continue translating the mRNA and will produce a protein that is too long. Second, the stop codons help to prevent mistakes in protein synthesis. If there is a mistake in the DNA code, the stop codons will ensure that the protein is not made.

The stop codons are also important for another reason. In addition to stopping protein synthesis, the stop codons can also activate a process known as nonsense-mediated mRNA decay (NMD). NMD is a process that targets mRNA for destruction if it contains a premature stop codon. NMD is important for two reasons. First, it helps to ensure that proteins are made correctly. Second, it helps to prevent the synthesis of proteins that could be harmful to the cell.

The stop codons

Broaden your view: Strongest Acid

What is the difference between a stop codon and a nonsense codon?

A stop codon is a sequence of three nucleotides that does not code for an amino acid and signals the end of protein synthesis. A nonsense codon is a sequence of three nucleotides that codes for a stop codon.

What happens when a stop codon is encountered?

When a stop codon is encountered, the ribosome will release the polypeptide chain and dissociate from the mRNA. The mRNA will then be free to be recycled and used again to produce proteins.

How does the ribosome know when to stop translating?

The ribosome is a large complex of proteins and RNA that serves as the site of protein synthesis in all living cells. The ribosome reads the genetic code in messenger RNA (mRNA) and translates it into a protein. The ribosome uses tRNA (transfer RNA) molecules to bring amino acids to the ribosome and assemble them into proteins according to the mRNA sequence.

The ribosome knows when to stop translating an mRNA molecule when it encounters a stop codon. A stop codon is a sequence of three nucleotides (UAA, UAG, or UGA) that does not code for an amino acid. When the ribosome reaches a stop codon, it releases the newly synthesized protein and dissociates from the mRNA molecule.

The ribosome can also stall during translation if it encounters an unusual sequence in the mRNA. For example, the ribosome may encounter a long stretch of uninterrupted RNA that does not code for an amino acid. In these cases, the ribosome will stall and wait for the cell to provide it with the necessary amino acids to continue translation.

It is also possible for the ribosome to make mistakes during translation. These mistakes can happen if the ribosome misreads the mRNA sequence or if the tRNA molecules bring the wrong amino acids to the ribosome. Most of these mistakes are corrected by other proteins in the cell before the protein is released from the ribosome.

Is there any way to override a stop codon?

A stop codon is a codon (a sequence of three nucleotides) that does not code for an amino acid, but instead signals the termination of protein synthesis. When a stop codon is encountered by a ribosome during translation, protein synthesis is halted. Although most stop codons are read by the ribosome as "UAA" or "UGA", there are three other stop codons in addition to these two. Stop codons are also referred to as "nonsense codons".

Since stop codons do not encode for an amino acid, they are not recognized by tRNA. Therefore, when a stop codon is encountered by the ribosome, there is no amino acid to be added to the polypeptide chain. The only way to override a stop codon is by using a mutant tRNA that recognizes the stop codon as an amino acid codon. This mutant tRNA is then able to add the amino acid to the polypeptide chain, allowing protein synthesis to continue.

The use of mutant tRNAs to override stop codons is known as "suppression". Suppression can be either spontaneous or induced. Spontaneous suppression occurs when a stop codon appears in the genome of an organism and a mutant tRNA arises that recognizes the stop codon as an amino acid codon. This mutant tRNA is then able to continues protein synthesis. Induced suppression occurs when a stop codon is artificially introduced into the genome of an organism and a mutant tRNA is generated in order to override the stop codon.

There are two types ofinduced suppression: Amber suppression and Ochre suppression. Amber suppression occurs when a UAG stop codon is introduced into the genome and a mutant tRNA that recognizes UAG as the amino acid tyrosine is generated. Ochre suppression occurs when a UAA or UGA stop codon is introduced into the genome and a mutant tRNA that recognizes UAA or UGA as the amino acid phenylalanine is generated.

Amber and ochre suppression can be used to artificially create proteins with amino acid sequences that would not otherwise be possible. For example, by using amber suppression, it is possible to create a protein with the amino acid sequence Tyr-Gly-Asp-Asn. This amino acid sequence is not found in any natural proteins, but is found in certain peptides that are

What happens if a stop codon is mutated?

A stop codon is a sequence of three nucleotides that does not code for an amino acid and signals the end of protein synthesis. If a stop codon is mutated, it can lead to several consequences, depending on where the mutation occurs.

If the mutation occurs in the coding region of a gene, it may change the amino acid that is encoded at that position. This can alter the protein's structure and function. If the mutated amino acid is essential for the protein's function, the protein may be nonfunctional.

If the mutation occurs in the promoter region of a gene, it may affect the transcription of the gene. This can lead to a decrease in the amount of protein produced.

If the mutation occurs in the regulatory region of a gene, it may affect the activity of the protein. For example, a mutation in the regulatory region of a gene that codes for a enzyme involved in blood clotting may reduce the activity of the enzyme, leading to a greater risk of bleeding.

While mutations in stop codons can have serious consequences, it is important to remember that most mutations are neutral or have little effect.

What is the difference between a stop codon and a frameshift mutation?

A stop codon is a sequence of three nucleotides that does not code for an amino acid and signals the end of protein synthesis. A frameshift mutation is a change in the DNA sequence that inserts or deletes a nucleotide, resulting in a shift in the reading frame.

What are the consequences of a stop codon mutation?

A stop codon mutation is a mutation that causes a change in one of the three stop codons, which are UAA, UAG, or UGA. This can result in the premature termination of protein synthesis, and can have a variety of consequences depending on where the mutation occurs.

If the mutation occurs in a gene that is essential for survival, it is likely to be fatal. For example, a mutation in the gene that encodes for the protein dystrophin causes Duchenne muscular dystrophy, which is a fatal disease.

If the mutation occurs in a non-essential gene, the consequences will depend on the function of the protein that is encoded by the gene. For example, a mutation in the gene that encodes for the protein hemoglobin can cause sickle cell disease, which is a serious and debilitating disease.

In some cases, a stop codon mutation may have no observable consequences. This is because the protein encoded by the gene may be able to function normally even if there is a change in one of the stop codons.

Overall, the consequences of a stop codon mutation can be varied and depending on the gene that is affected, can range from having no observable consequences to being fatal.

Frequently Asked Questions

What are the three stop codons in DNA?

There are three stop codons in DNA. These are UAG (amber), UAA (ochre) and UGA (opal).

What would happen if there were no stop codons?

In a situation without stop codons, the body would continue to read the mRNA and attach amino acids. The proteins would then be nonfunctional because they are too large.

Which codon is used to specify methionine?

The use of UUG codon to specify methionine is the most common.

What are the stop codons?

The three STOP codons have been named as amber (UAG), opal or umber (UGA) and ochre (UAA). "Amber" or UAG was discovered by Charles Steinberg in 1952, "Opal" or UGA was first identified by Ronald George Denney in 1968, and "Ochre" or UAA was found by Sydney Brenner in 1971.

How many codons do not specify amino acids?

There are three other codons that do not specify amino acids. These are called stop codons and signify when a protein is complete.

Mollie Sherman

Writer

Mollie Sherman is an experienced and accomplished article author who has been writing for over 15 years. She specializes in health, nutrition, and lifestyle topics, with a focus on helping people understand the science behind everyday decisions. Mollie has published hundreds of articles in leading magazines and websites, including Women's Health, Shape Magazine, Cooking Light, and MindBodyGreen.

Love What You Read? Stay Updated!

Join our community for insights, tips, and more.